Endocrine Abstracts

Introduction: Thyroid incidentaloma detected by FDG-PET/CT (flourodeoxyglucose positron emition tomography/computed tomography) is important because of high rate of malignancy. Elastosonograpghy has proven valuable in discriminating malign and benign thyroid lesions. In this study, we aimed to evaluate PET incidentalomas by ultrasonography and elastosonography and to compare cytopathological results with imaging findings.Methods: A total of 50 patients i...

Introduction: Vitamin D deficiency is a common health problem. Vitamin D supplements are used to improve vitamin D status. However, there are few data about what doses to give and how often to give. The aim of this study is to determine the effects of single high dose or daily low dose oral cholecalciferol (vitamin D3) on vitamin D levels and muscle strenght.Methods and design: 60 healthy postmenouposal women who had serum vitamin D levels wer...

Introduction: The relationship between hyperthyroidism and voice disorders has not been identified before. The aim of this study was to investigate the changes in the acoustic values in patients with subclinical thyrotoxicosis.Methods: In this study, acoustic voice analysis was evaluated in a total of 115 cases. Sixty of 115 individuals (18 men and 42 women) had subclinical thyrotoxicosis, aged between 18 and 65 years, and all had no history of laryngeal...

Introduction: Levothyroxine sodium (LT4) is widely used thyroid hormone to treat hypothyroidism. It is generally recommended to take it in the morning and hungry. Several studies about timing of thyroid hormone administration have shown different effects on TSH and FT4. The aim of this study is to determine the effects of timing of LT4 administration on TSH and the clinical outcomes.Method: The study group includes 65 pat...

Aims: Primary hyperparathyroidism (PH) has been reported to be associated with increased insulin resistance, hypertension, dyslipidemia and cardiovascular inflammatory markers. The aims of this study were to evaluate the rate of metabolic syndrome (MS) and effect of parathormone, calcium and phosphorus levels to MS components in PH subjects.Methods: One hundred and fifty one subjects, 23 men and 128 women, aged 53±11.2 years with newly diagnosed PH ...

Introduction: Paragangliomas are neuroendocrine tumors arising from extra-adrenal chromaffin cells. Paragangliomas of the head and neck frequently originate from the paraganglionic system including the carotid bifurcation, middle ear and the ganglion nodosum of the vagus nerve. However, of paragangliomas of the head and neck, only 1–3% secrete hormones and majority are non-functional. Here, we describe a case of non-functional paraganglioma confused with parathyroid adeno...

Introduction: While mediastinal parathyroid carcinoma is a rare entity by itself, multiglandular coexistence of parathyroid carcinoma and adenoma represents an extremely rare condition. Herein, we report such a rare presentation of multiglandular parathyroid neoplasm with an ectopic carcinoma in the mediastinum and adenoma on the right side of neck in a patient with persistent primary hyperparathyroidism (PHP).Case report: A 38-year-old female patient wh...

Aim: Cardiac rhythm abnormalities have been documented in acromegalic patients. Our aim is to evaluate atrial electromechanical delay (EMD) with tissue doppler imaging (TDI) in patients with acromegaly.Material and methods: Fourty patients with acromegaly (13 patients with remission disease and 27 patients with active disease; 22 women and 18 men; mean aged 46.1±10.3 years), and 37 age- and sex-matched healthy controls were enrolled in the study. At...

The relation between obesity and diabetes mellitus is known for long periods and this relation is based on insulin resistance. Recent studies showed that epicardial adipose tissue thickness measured by echocardiography is the marker of the visceral adipose tissue and cardiovascular risk. Visfatin is a new described adipokine and it has been showed to have mRNA expression in epicardial adipose tissue. There is a conflict about the role of visfatin on obesity, insulin resistance...

BackgroundPrimary hyperparathyroidism (PHPT) is known to be associated with cardiac and metabolic morbidities. Chronic hypercalcemia in PHPT patients has been reported to be associated with an increased risk of mortality, particularly due to cardiovascular disease, during long-term follow-up. Endocan is secreted by vascular endothelial cells and is involved in the regulation of important endothelial functions. Endocan secretion increases in a variety of ...